Reducing the risk of stomach ulcers in certain patients who take nonsteroidal anti-inflammatory drugs (NSAIDs). It may also be used for other conditions as determined by your doctor. Misoprostol is a prostaglandin. It works by reducing the amount of acid released by the stomach and protecting the stomach lining, which helps to reduce the risk of stomach ulcers.

you are allergic to any ingredient in misoprostol or to similar medicines (prostaglandins) you are pregnant Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with misoprostol. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you: if you are planning to become pregnant or are breast-feeding if you are able to become pregnant if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement if you have allergies to medicines, foods, or other substances if you have a history of heart disease, inflammatory bowel disease (eg, irritable bowel syndrome), dehydration, or other problems that may be worsened if you become dehydrated Some MEDICINES MAY INTERACT with misoprostol. However, no specific interactions with misoprostol are known at this time. Ask your health care provider if misoprostol may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Use misoprostol as directed by your doctor. Check the label on the medicine for exact dosing instructions. An extra patient leaflet is available with misoprostol. Talk to your pharmacist if you have questions about this information. Take misoprostol by mouth with food unless your doctor tells you otherwise. The last dose of the day should be taken at bedtime. Taking misoprostol after meals and at bedtime may decrease the risk of diarrhea. Do not take an antacid that has magnesium in it within 1 hour before or 2 hours after you take misoprostol. If you miss a dose of misoprostol, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once. Ask your health care provider any questions you may have about how to use misoprostol.